keywords: Clariasgariepinus, degenerative inflammation, gastrointestinal tract, hemorrhage, necrosis, toxicant
The acute toxicity test of lead to Clariasgariepinus juveniles and the rate of bioaccumulation in the intestine of Clariasgariepinus juveniles was investigated by Standard Methods by APHA (2000). At the end of the 96 hours the gastrointestinal tract were rinsed in 10% formalin and preserved for further analysis. In this study, the LC50 values of Clariasgariepinus at 96 h period was determined to be 50.118 ppm or 50.12 mg/ L. Results obtained from this study showed that lead (Pb(NO3)2) has extensive histological changes in the gastrointestinal tract exposed to the various lead concentrations of 100 mgL-1, 75 mgL-1 and 50 mgL-1. The lead concentration disturbed the homeostasis and led to physiological disorders in their functions and subsequently to the death of the juveniles Clariasgariepinus. The effects of toxicant on the gastrointestinal tract of fish on this study ranged from slight changes in motility, secretion and absorptive functions to more severe effects associated with mucosal integrity, blood flow and impacted neuromuscular control.
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