FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

(A Peer Review Journal)
e–ISSN: 2408–5162; p–ISSN: 2048–5170

FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

STUDIES ON THE ROLE OF Escherichia coli IN PREGNANCY RELATED MISCARRIAGES (SPONTANEOUS ABORTIONS) IN UPLAND AREA OF RIVERS STATE OF NIGERIA
Pages: 377-380
G. I. Okoroiwu and C. K. Wachukwu


keywords: Miscarriage, Escherichia coli, endocervical smear, urine, upland

Abstract

Escherichia coli infection is a serious health threat to the ordinary people, especially the intending mothers all over the world, but more so in the developing countries. In this cohort study, 300 Endocervical swabs (ECS) and mid-stream urine (MSU) samples were collected within 8 hours to 24 h of miscarriages to determine the prevalence and role of Escherichia coli in pregnancy related miscarriages in the Upland Area of Rivers state, in this era of frequent miscarriages amongst Women. The ECS were cultured on chocolate, blood and MacConkey agar while MSU samples were inoculated on MacConkey and CLED media, respectively. The growths were isolated and characterized using biochemical activities including fermentation, Gram reaction, motility, colonial appearance, media selection. ECS samples were also screened for Chlamydia trachomatis using Chlamydia Rapid Test Device kit. Of the 130 isolates 54(41.5%) of them were Escherichia coli while the proportions of the infected women were highest within the 18-20 years and 21 – 25 years age cohorts (P<0.05). The prevalence of Escherichia coli showed significant relationship (p<0.05) with the illiteracy level of the women, more so, the level of this result statistically (p<0.05) associates Escherichia coli with miscarriages in the Upland area of Rivers state of Nigeria, and this calls for mass literacy and awareness among the intending mothers.

References

Baker FJ, Silverton RE & Pallister CJ 2011. Introduction to Medical Laboratory Technology. 7th edition, Arnold, Bounty Press Ltd. Chessbrough M 2000. District Laboratory Practice in Tropical Countries (Part 2). Cambridge University Press. Chiwuzie J, Braimah S, Unuigbe J & Olumeko P 1995. Causes of maternal mortality in a Semi-urban Nigerian setting. World Health Forum, 16(4): 20-25. David J & Steer P 2010. High Risk pregnancy ,management options. Elsevier Saunders. Delzell JE & Lefevre ML 2000. Urinary Tract Infections during pregnancy. American Family Physcian, 61: 713-21. Greenwood B 1999. Meningococcal meningitis in Africa. Transaction of the Royal Society of Tropical Medicine and Hygiene, 93: 341-353. John S 2016.The role of Listeria monocytogenes and other bacteriae in meningitis and Spontaneous abortions in some towns in Northern Nigeria. Ph.D thesis. Joseph N 2014.What is miscarriage? What causes miscarriage? Medical News Today. Konge JC 1986. Septic abortions in Ibadan. Dissertation. Nigerian Postgraduate Medical College. Khong TY, Frappell JM, Steel HM, Stewart CM & Burke M 1986.Perinatal Listeriosis. British J. Obstetrics & Gynaecol., 93: 1083-1087. Lwin MM, DeLouvois J & Hurley DR 1991. Carriage of Listeria monocytogenes in pregnant women. J. Obstetrics & Gynaecology, 2: 41-42. McCormick T, Ashe RG & Kearny PM 2008. Urinary Tract Infections in pregnancy. Obstetrician and Gynaecologist, 10: 156-162. Mills JL, Simpson JL, Driscoll SG, Jovanovic-Peterson L, Ven Allen M, Aaron JH, Metzger B Bieber FR, Knopp RH & Holmes LB 1988. Incidence of spontaneous abortions among normal women and Insulin-Dependent Diabetic Women whose pregnancies were identified within 21 days of conception. New Engl. J. Medicine, 319(25): 1617-23. Mirdamadi S 2005. Immunological and microbiological study of abortion samples for serotype determination of Listeria monocytogenes in Iran. Eur. Soc. Clin. Microbio. & Infectious Diseases,24: 1245-1345. Nnanda K, Lopez LM & Grimes DA 2012. Expectant care versus surgical treatment for miscarriages. Cochrane Database Syst. Rev., 14: 3. Novak J & Broom B 1999. Materna and Child Health Nursing. Mosby Inc.

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