keywords: Annona muricata, antibacterial, leaf, phytochemicals, seed, ethanol extract
Annona muricata belongs to the Annonaceous family which has been of great importance to humans since ancient times. Soursop have contributed to the world pharmacologically in providing antimicrobial, anti-arthritis, antioxidant, anti-inflammation and anticancer properties beneficial to man. The research was conducted to determine the phytochemical screening and antibacterial activity of ethanol extract of the leaf and seed of Annona muricata Linn (Soursop). The phytochemical screening and antibacterial activity were done according to standard methods. Terpenoid and flavonoid were present while the antibacterial activity indicated zones of inhibition at a concentration of 100 mg/ml; 28 mm (Staphylococcus aureus), 11 mm (Streptococcus mutant), 16 mm (Pseudomonas aeroginosa) and 25 mm (Eschericha coli) for the seed extract. The leaf indicated a dose dependent activity when compared to ciprofloxacin. The study has shown that the extracts of A. muricata contained rich bioactive chemical constituents with significant antibacterial activity.