Abstract

Albinism an autosomal recessive allele is a disease characterized by lack of pigmentation in the eye, skin and hair. Albinism allelic frequency was estimated by counting the number of albinos per 10,000 individuals in the Cities (Kano, Kaduna, Sokoto, Gusau and Minna) of Northern guinea savannah. The allelic frequency was low, with range 0.013 to 0.011. Kano population has a frequency of 0.013, Kaduna and Minna 0.012, Sokoto and Gusau 0.011, respectively. For the genotypic frequencies, homozygous recessive genotype was found to 0.016%, the heterozygous genotype was 2.5% and the homozygous dominant genotype was 97.2% in Kano population. In Kaduna and Minna populations, homozygous recessive has 0.014%, heterozygous has 2.3% and homozygous dominant genotype has 97.4%, while homozygous recessive has 0.012%, the heterozygous genotype has 2.1% and homozygous dominant has 97.6% in Sokoto and Gusau populations. In conclusion the allele has a low frequency within the sub region, which could be as a result of purifying selection and mate preference in the populations.