Abstract

Antimicrobial resistance (AMR) presents a serious risk to public health worldwide, requiring effective management strategies in healthcare facilities. Healthcare-associated infections, including those caused by multidrug-resistant organisms (MDROs), are major drivers of AMR in healthcare facilities, and may be significantly influenced by hospital transfers within or between healthcare units and regions. Challenges in managing AMR in healthcare facilities include inappropriate and suboptimal antibiotic prescription practices, the evolution of multidrug resistant organisms, AMR healthcare-associated infections, poor compliance with infection prevention and control measures, and non-implementation of antimicrobial stewardship programs. AMR can be successfully managed in healthcare facilities by implementing antimicrobial stewardship programs, adherence to infection prevention and control measures, surveillance and monitoring of AMR trends, and innovations in diagnostics and therapeutics for AMR.